Pick it up, or Let it Go

There are somethings and some people, and some relationships and friendships you just have to let go, some are there for a reason and some are there for a season and maybe even a lifetime. But there comes a time where you just have to let go and give each other space to breath. There may come a time where you may com back together, but can you pick it up? ( The relationship, friendship) where it left off at or is just time for you to let it go?